Comparison between microsphere-assisted and confocal microscopies

Arash Darafsheh, Nicholaos I. Limberopoulos, John S. Derov, Dennis E. Walker, Vasily N. Astratov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

We show that microsphere-assisted microscopy, where liquid-immersed barium titanate glass (n ∼ 1.9) beads with diameters of several microns are employed, has superior optical resolution compared to the confocal microscopy. The resolution advantage of microsphere-assisted microscopy stems from an ability of high-index microspheres to pick spatial distribution of optical near-fields produced by the plasmonic nanostructure used in our experiments. It is shown that an additional advantage of imaging through liquid-immersed microspheres is the ability to achieve high resolution imaging using microscope objectives with moderate numerical apertures. This means that microsphere-assisted microscopy can be performed with longer working distances compared to conventional or confocal microscopy. Super-resolution microscopy by using liquid-immersed microspheres can be potentially used in biomedical microscopy, microfluidics, and nanophotonics applications.

Original languageEnglish
Title of host publication2013 15th International Conference on Transparent Optical Networks, ICTON 2013
DOIs
StatePublished - Oct 15 2013
Externally publishedYes
Event2013 15th International Conference on Transparent Optical Networks, ICTON 2013 - Cartagena, Spain
Duration: Jun 23 2013Jun 27 2013

Publication series

NameInternational Conference on Transparent Optical Networks
ISSN (Electronic)2162-7339

Conference

Conference2013 15th International Conference on Transparent Optical Networks, ICTON 2013
CountrySpain
CityCartagena
Period06/23/1306/27/13

Keywords

  • Super-resolution
  • confocal
  • imaging
  • microscopy
  • photonic nanojet
  • subdiffraction resolution

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  • Cite this

    Darafsheh, A., Limberopoulos, N. I., Derov, J. S., Walker, D. E., & Astratov, V. N. (2013). Comparison between microsphere-assisted and confocal microscopies. In 2013 15th International Conference on Transparent Optical Networks, ICTON 2013 [6602909] (International Conference on Transparent Optical Networks). https://doi.org/10.1109/ICTON.2013.6602909