TY - JOUR
T1 - Comparing clinical bladder diaries and recalled patient reports for measuring lower urinary tract symptoms in the symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
AU - LURN Study Group
AU - Flynn, Kathryn E.
AU - Wiseman, Jonathan B.
AU - Helmuth, Margaret E.
AU - Smith, Abigail R.
AU - Bradley, Catherine S.
AU - Cameron, Anne P.
AU - Henry Lai, H.
AU - Kirkali, Ziya
AU - Kreder, Karl J.
AU - Geynisman-Tan, Julia
AU - Merion, Robert M.
AU - Weinfurt, Kevin P.
N1 - Funding Information:
Heather Van Doren, Senior Medical Editor with Arbor Research Collaborative for Health, provided editorial assistance on this manuscript. This is publication number 29 of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN). This study is supported by the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) through cooperative agreements (grants DK097780, DK097772, DK097779, DK099932, DK100011, DK100017, DK099879). Research reported in this publication was supported at Northwestern University, in part, by the National Institutes of Health's (NIH's) National Center for Advancing Translational Sciences (NCATS), grant UL1TR001422. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Funder NIDDK had the following role in conceptualization, design, data collection, analysis, decision to publish, preparation of the manuscript: This paper is the product of a cooperative agreement (U01 as grant mechanism [grant numbers provided in paragraphs above]). Thus requires the involvement of coauthor Ziya Kirkali, MD, NIH/NIDDK Project Scientist, in the multiple roles defined above within this statement. Funder NCATS had no role in the conceptualization, design, data collection, analysis, decision to publish, or preparation of the manuscript. The following individuals were instrumental in the planning and conduct of this study at each of the participating institutions: Duke University, Durham, North Carolina (DK097780): PIs: Cindy Amundsen, MD, Eric Jelovsek, MD; Co‐Is: Kathryn Flynn, PhD, Todd Harshbarger, PhD, Jim Hokanson, PhD, Aaron Lentz, MD, Michelle O'Shea, MD, David Page, PhD, Nazema Siddiqui, MD, Kevin Weinfurt, PhD Lisa Wruck, PhD; Study Coordinators: Yasmeen Bruton, Paige GreenUniversity of Iowa, Iowa City, IA (DK097772): PIs: Catherine S. Bradley, MD, Karl Kreder, MD, MBA, MSCE; Co‐Is: Bradley A. Erickson, MD, MS, Daniel Fick, MD, Vince Magnotta, PhD, Philip Polgreen, MD, MPH; Study Coordinators: Mary Eno, Sarah Heady, Chelsea Poesch. Northwestern University, Chicago, IL (DK097779): PIs: James W Griffith, PhD, Kimberly Kenton, MD, MS, Brian Helfand, MD, PhD; Co‐Is: Carol Bretschneider, MD, David Cella, PhD, Sarah Collins, MD, Julia Geynisman‐Tan, MD, Alex Glaser, MD, Christina Lewicky‐Gaupp, MD, Margaret Mueller, MD; Study Coordinators: Sylwia Clarke, Melissa Marquez, Pooja Sharma, Michelle Taddeo, Pooja Talaty. Dr. Helfand and Ms. Talaty are at NorthShore University HealthSystem. University of Michigan Health System, Ann Arbor, MI (DK099932): PI: J. Quentin Clemens, MD, FACS, MSCI; Co‐Is: John DeLancey, MD, Dee Fenner, MD, Rick Harris, MD, Steve Harte, PhD, Anne P. Cameron, MD, Aruna Sarma, PhD, Giulia Lane, MD; Study Coordinators: Ashly Chimner, Linda Drnek, Emma Keer, Marissa Moore, Greg Mowatt, Sarah Richardson. University of Washington, Seattle Washington (DK100011): PI: Claire Yang, MD; Co‐I: Anna Kirby, MD; Study Coordinators: Lois Meryman, Brenda Vicars, RN. Washington University in St. Louis, St. Louis Missouri (DK100017): PI: H. Henry Lai, MD; Co‐Is: Gerald L. Andriole, MD, Joshua Shimony, MD, PhD; Study Coordinators: Linda Black, Vivien Gardner, Patricia Hayden, Diana Wolff, Aleksandra Klim, RN, MHS, CCRC. Arbor Research Collaborative for Health, Data Coordinating Center (DK099879): PI: Robert Merion, MD, FACS; Co‐Is: Victor Andreev, PhD, DSc, Brenda Gillespie, PhD, Abigail Smith, PhD; Project Manager: Melissa Fava, MPA, PMP; Clinical Monitor: Melissa Sexton, BA, CCRP; Research Analysts: Margaret Helmuth, MA, Jon Wiseman, MS, Jane Liu, MPH; Project Associate: Levi Hurley. National Institute of Diabetes and Digestive and Kidney Diseases, Division of Kidney, Urology, and Hematology, Bethesda, MD: Project Scientist: Ziya Kirkali MD; Project Officer: Christopher Mullins PhD; Project Advisor: Julie Barthold, MD.
Publisher Copyright:
© 2022 Wiley Periodicals LLC.
PY - 2022/11
Y1 - 2022/11
N2 - Purpose: Bladder diaries are a key source of information about lower urinary tract symptoms (LUTS); however, many patients do not complete them as instructed. Questionnaire-based patient-reported outcome measures (PROMs) are another option for reporting LUTS but may have recall bias. We assessed the strength of the associations between PROMs and a 3-day bladder diary. Materials and Methods: Symptomatic adults from 6 tertiary care sites completed a 3-day paper bladder diary and 3-, 7-, and 30-day electronic PROMs. We assessed the linear associations between mapped pairs of diary variables and responses to PROM items using biserial and polyserial correlation coefficients with 95% confidence intervals. Results: Of 290 enrolled participants, 175 (60%) completed the bladder diary as instructed and at least one corresponding PROM. Linear associations were strongest between the diary and 3-day recall of daytime frequency (r = 0.75) and nighttime frequency (r = 0.69), followed by voids with urgency sensations (r = 0.62), and an item reporting any incontinence (r = 0.56). Linear associations between bladder diary and specific incontinence variables (e.g., stress, urgency) were low to negligible (ranging from r = 0.16–0.39). Linear associations were consistent across the 3-, 7-, and 30-day recall periods. Conclusions: Missing and unusable bladder diary data were common, highlighting the patient burden associated with this method of data collection. A questionnaire-based PROM is a reasonable alternative to a diary for reporting voiding frequency and may offer an easier option for reporting some symptoms.
AB - Purpose: Bladder diaries are a key source of information about lower urinary tract symptoms (LUTS); however, many patients do not complete them as instructed. Questionnaire-based patient-reported outcome measures (PROMs) are another option for reporting LUTS but may have recall bias. We assessed the strength of the associations between PROMs and a 3-day bladder diary. Materials and Methods: Symptomatic adults from 6 tertiary care sites completed a 3-day paper bladder diary and 3-, 7-, and 30-day electronic PROMs. We assessed the linear associations between mapped pairs of diary variables and responses to PROM items using biserial and polyserial correlation coefficients with 95% confidence intervals. Results: Of 290 enrolled participants, 175 (60%) completed the bladder diary as instructed and at least one corresponding PROM. Linear associations were strongest between the diary and 3-day recall of daytime frequency (r = 0.75) and nighttime frequency (r = 0.69), followed by voids with urgency sensations (r = 0.62), and an item reporting any incontinence (r = 0.56). Linear associations between bladder diary and specific incontinence variables (e.g., stress, urgency) were low to negligible (ranging from r = 0.16–0.39). Linear associations were consistent across the 3-, 7-, and 30-day recall periods. Conclusions: Missing and unusable bladder diary data were common, highlighting the patient burden associated with this method of data collection. A questionnaire-based PROM is a reasonable alternative to a diary for reporting voiding frequency and may offer an easier option for reporting some symptoms.
KW - lower urinary tract symptoms
KW - measurement
KW - mental recall
KW - patient-reported outcomes
KW - self-report
KW - urination
UR - http://www.scopus.com/inward/record.url?scp=85138368211&partnerID=8YFLogxK
U2 - 10.1002/nau.25030
DO - 10.1002/nau.25030
M3 - Article
C2 - 36066068
AN - SCOPUS:85138368211
VL - 41
SP - 1711
EP - 1721
JO - Neurourology and Urodynamics
JF - Neurourology and Urodynamics
SN - 0733-2467
IS - 8
ER -