@inproceedings{943640116d38425b9f8d73f51992dafe,
title = "Compact intraoperative imaging device for sentinel lymph node mapping",
abstract = "We have developed a novel real-time intraoperative fluorescence imaging device that can detect near-infrared (NIR) fluorescence and map sentinel lymph nodes (SLNs). In contrast to conventional imaging systems, this device is compact, portable, and battery-operated. It is also wearable and thus allows hands-free operation of clinicians. The system directly displays the fluorescence in its goggle eyepiece, eliminating the need for a remote monitor. Using this device in murine lymphatic mapping, the SLNs stained with indocyanine green (ICG) can be readily detected. Fluorescence-guided SLN resection under the new device was performed with ease. Ex vivo examination of resected tissues also revealed high fluorescence level in the SLNs. Histology further confirmed the lymphatic nature of the resected SLNs.",
keywords = "Cancer staging, Fluorescence imaging, Indocyanine green, Intraoperative imaging, Sentinel lymph node",
author = "Yang Liu and Bauer, {Adam Q.} and Walter Akers and Gail Sudlow and Kexian Liang and Duanwen Shen and Mikhail Berezin and Culver, {Joseph P.} and Samuel Achilefu",
year = "2011",
doi = "10.1117/12.886226",
language = "English",
isbn = "9780819484475",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III",
note = "Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III ; Conference date: 24-01-2011 Through 26-01-2011",
}