TY - JOUR
T1 - Comorbid Sleep Disturbances in Neurologic Disorders
AU - Ju, Yo El S.
AU - Videnovic, Aleksandar
AU - Vaughn, Bradley V.
N1 - Publisher Copyright:
© 2017 American Academy of Neurology.
PY - 2017/8/1
Y1 - 2017/8/1
N2 - Purpose of Review: This article provides a review of disturbances of sleep comorbid with common neurologic disorders. Recent Findings: A wide variety of neurologic disorders are frequently complicated by comorbid sleep disturbances. In many cases, a bidirectional relationship appears to occur between sleep function and the neurologic disease, such that treatment of comorbid sleep disturbances may improve the symptoms of the neurologic disease. Summary: Neurologic disorders are often associated with abnormalities of sleep. Sleep influences the severity of both epilepsy and headache, and treatment of comorbid sleep disorders may improve seizure and headache frequency. Alzheimer disease is characterized by circadian phase delay and poor nighttime sleep and is strongly associated with obstructive sleep apnea. Parkinson disease is associated with several sleep disorders, including insomnia, restless legs syndrome, rapid eye movement (REM) sleep behavior disorder, daytime hypersomnia, and sleep-disordered breathing. Hypoventilation in amyotrophic lateral sclerosis and other neuromuscular disorders often presents initially with sleep problems, and treatment with noninvasive ventilation improves survival and quality of life.
AB - Purpose of Review: This article provides a review of disturbances of sleep comorbid with common neurologic disorders. Recent Findings: A wide variety of neurologic disorders are frequently complicated by comorbid sleep disturbances. In many cases, a bidirectional relationship appears to occur between sleep function and the neurologic disease, such that treatment of comorbid sleep disturbances may improve the symptoms of the neurologic disease. Summary: Neurologic disorders are often associated with abnormalities of sleep. Sleep influences the severity of both epilepsy and headache, and treatment of comorbid sleep disorders may improve seizure and headache frequency. Alzheimer disease is characterized by circadian phase delay and poor nighttime sleep and is strongly associated with obstructive sleep apnea. Parkinson disease is associated with several sleep disorders, including insomnia, restless legs syndrome, rapid eye movement (REM) sleep behavior disorder, daytime hypersomnia, and sleep-disordered breathing. Hypoventilation in amyotrophic lateral sclerosis and other neuromuscular disorders often presents initially with sleep problems, and treatment with noninvasive ventilation improves survival and quality of life.
UR - http://www.scopus.com/inward/record.url?scp=85026864147&partnerID=8YFLogxK
U2 - 10.1212/CON.0000000000000501
DO - 10.1212/CON.0000000000000501
M3 - Review article
C2 - 28777179
AN - SCOPUS:85026864147
SN - 1080-2371
VL - 23
SP - 1117
EP - 1131
JO - CONTINUUM Lifelong Learning in Neurology
JF - CONTINUUM Lifelong Learning in Neurology
IS - 4, SleepNeurology
ER -