Community acquired respiratory viral infections after lung transplantation: Clinical features and long-term consequences

Murali M. Chakinala, Michael J. Walter

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Community acquired respiratory viruses (CARVs) are increasingly recognized as serious threats to lung transplant recipients. While CARVs such as respiratory syncytial virus, parainfluenza, influenza, and adenovirus usually cause self-limited illnesses in immunocompetent subjects, infections in the transplant recipient can be dramatic. As transplant recipients live longer and diagnostic methods improve, the burden of CARVs will undoubtedly increase. Because of limited therapeutic options, some patients may succumb to CARV infections, while many survivors develop chronic allograft dysfunction. Recognition of this latter phenomenon has implicated CARVs in the pathogenesis of bronchiolitis obliterans.

Original languageEnglish
Pages (from-to)342-349
Number of pages8
JournalSeminars in Thoracic and Cardiovascular Surgery
Volume16
Issue number4
DOIs
StatePublished - Dec 1 2004

Keywords

  • Bronchiolitis obliterans syndrome
  • Community acquired respiratory virus
  • Parainfluenza
  • Pneumonia
  • Respiratory syncytial virus

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