TY - JOUR
T1 - Comment on "Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI" and "Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area"
AU - Astafiev, Serguei V.
AU - Snyder, Abraham Z.
AU - Shulman, Gordon L.
AU - Corbetta, Maurizio
PY - 2010/4/16
Y1 - 2010/4/16
N2 - Minzenberg et al (Reports, 12 December 2008, p. 1700) and Schmidt ef al. (Reports, 24 April 2009, p. 516) reported blood oxygen level-dependent (BOLD) responses in the human locus coeruleus (LC). Here, we show that these LC responses do not correspond to the anatomical location of the LC and present cautionary data concerning the quality of BOLD signals measured from the LC using standard functional magnetic resonance imaging acquisition parameters.
AB - Minzenberg et al (Reports, 12 December 2008, p. 1700) and Schmidt ef al. (Reports, 24 April 2009, p. 516) reported blood oxygen level-dependent (BOLD) responses in the human locus coeruleus (LC). Here, we show that these LC responses do not correspond to the anatomical location of the LC and present cautionary data concerning the quality of BOLD signals measured from the LC using standard functional magnetic resonance imaging acquisition parameters.
UR - http://www.scopus.com/inward/record.url?scp=77951147324&partnerID=8YFLogxK
U2 - 10.1126/science.1177200
DO - 10.1126/science.1177200
M3 - Comment/debate
C2 - 20395497
AN - SCOPUS:77951147324
VL - 328
SP - 309-a
JO - Science
JF - Science
SN - 0036-8075
IS - 5976
ER -