Comment on "Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI" and "Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area"

Serguei V. Astafiev, Abraham Z. Snyder, Gordon L. Shulman, Maurizio Corbetta

Research output: Contribution to journalComment/debate

51 Scopus citations

Abstract

Minzenberg et al (Reports, 12 December 2008, p. 1700) and Schmidt ef al. (Reports, 24 April 2009, p. 516) reported blood oxygen level-dependent (BOLD) responses in the human locus coeruleus (LC). Here, we show that these LC responses do not correspond to the anatomical location of the LC and present cautionary data concerning the quality of BOLD signals measured from the LC using standard functional magnetic resonance imaging acquisition parameters.

Original languageEnglish
Pages (from-to)309-a
JournalScience
Volume328
Issue number5976
DOIs
StatePublished - Apr 16 2010

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