Come together, right...now: Synchronization of rhythms in a mammalian circadian clock

Sara J. Aton; Erik D. Herzog

doi:10.1016/j.neuron.2005.11.001

Come together, right...now: Synchronization of rhythms in a mammalian circadian clock

Sara J. Aton, Erik D. Herzog

Research output: Contribution to journal › Short survey › peer-review

240 Scopus citations

Abstract

In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant circadian pacemaker, coordinating rhythms throughout the body and regulating daily and seasonal changes in physiology and behavior. This review focuses on the mechanisms that mediate synchronization of circadian rhythms between SCN neurons. Understanding how these neurons communicate as a network of circadian oscillators has begun to shed light on the adaptability and dysfunction of the brain's master clock.

Original language	English
Pages (from-to)	531-534
Number of pages	4
Journal	Neuron
Volume	48
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2005.11.001
State	Published - Nov 23 2005

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abstract = "In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant circadian pacemaker, coordinating rhythms throughout the body and regulating daily and seasonal changes in physiology and behavior. This review focuses on the mechanisms that mediate synchronization of circadian rhythms between SCN neurons. Understanding how these neurons communicate as a network of circadian oscillators has begun to shed light on the adaptability and dysfunction of the brain's master clock.",

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N2 - In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant circadian pacemaker, coordinating rhythms throughout the body and regulating daily and seasonal changes in physiology and behavior. This review focuses on the mechanisms that mediate synchronization of circadian rhythms between SCN neurons. Understanding how these neurons communicate as a network of circadian oscillators has begun to shed light on the adaptability and dysfunction of the brain's master clock.

AB - In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant circadian pacemaker, coordinating rhythms throughout the body and regulating daily and seasonal changes in physiology and behavior. This review focuses on the mechanisms that mediate synchronization of circadian rhythms between SCN neurons. Understanding how these neurons communicate as a network of circadian oscillators has begun to shed light on the adaptability and dysfunction of the brain's master clock.

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Come together, right...now: Synchronization of rhythms in a mammalian circadian clock

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