Combinatorial assembly of neurons: from chromatin to dendrites

Luis de la Torre-Ubieta, Azad Bonni

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations


The generation and refinement of dendrites is essential for normal brain development and function. However, the molecular mechanisms that govern dendritic morphogenesis are poorly understood. Recent studies from the Crabtree laboratory have uncovered a requirement for the neuron-specific chromatin-remodeling enzyme nBAF in dendritic growth and branching in response to neuronal activity. These findings highlight the significance of epigenetic mechanisms in activity-dependent dendritic morphogenesis, with important implications in brain development and plasticity.

Original languageEnglish
Pages (from-to)48-51
Number of pages4
JournalTrends in Cell Biology
Issue number2
StatePublished - Feb 2008


Dive into the research topics of 'Combinatorial assembly of neurons: from chromatin to dendrites'. Together they form a unique fingerprint.

Cite this