Combination therapy for perianal squamous cell carcinoma in situ with imiquimod and photodynamic therapy

Nicholas M. Bontumasi, David Sheinbein, Eva A. Hurst

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Perianal squamous cell carcinoma in situ (SCCIS) is a relatively rare intraepidermal neoplasm that has the potential to progress to invasive squamous cell carcinoma. First-line treatment is surgical excision, though nonsurgical treatment modalities such as 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) and imiquimod also have been investigated for this neoplasm. Unfortunately, recurrences are known to occur after both surgical and nonsurgical monotherapies. We report a case of perianal SCCIS that was successfully treated with a novel combination of ALA-PDT and imiquimod.

Original languageEnglish
Pages (from-to)252-254
Number of pages3
JournalCutis
Volume94
Issue number5
StatePublished - Jan 1 2014

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