Coeliac disease presenting as severe hypoglycaemia in youth with Type 1 diabetes

N. Khoury, K. Semenkovich, A. M. Arbeláez

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background: Coeliac disease is an autoimmune disorder classically characterized by gastrointestinal symptoms and poor growth. The disease can be difficult to recognize in patients with Type 1 diabetes mellitus. Some clinicians find treatment of the disease in asymptomatic individuals controversial. Case reports: Two adolescent female patients with Type 1 diabetes experienced recurrent hypoglycaemic seizures. Neither patient reported gastrointestinal symptoms or poor growth. After diagnosis and treatment of coeliac disease, hypoglycaemia resolved. Conclusion: These cases illustrate how frequent unexplained severe hypoglycaemia can be an atypical presentation of coeliac disease in youth with Type 1 diabetes. Furthermore, they emphasize the importance of screening and treatment of coeliac disease in asymptomatic patients with Type 1 diabetes. Although controversial, management of coeliac disease in these asymptomatic patients can prevent the vicious cycle of recurrent hypoglycaemia and decrease risk for morbidity and death.

Original languageEnglish
Pages (from-to)e33-e36
JournalDiabetic Medicine
Issue number12
StatePublished - Dec 1 2014


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