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Cocaine abusers have an overexpression of α-synuclein in dopamine neurons
Deborah C. Mash
, Qinjie Ouyang
, John Pablo
, Margaret Basile
, Sari Izenwasser
, Abraham Lieberman
,
Richard J. Perrin
Division of Neuropathology
Institute of Clinical and Translational Sciences (ICTS)
Hope Center for Neurological Disorders
Research output
:
Contribution to journal
›
Article
›
peer-review
124
Scopus citations
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Keyphrases
Overexpression
100%
Alpha-synuclein (α-syn)
100%
Dopamine Neurons
100%
Cocaine
100%
Abusers
100%
Parkinson's Disease
25%
Substantia Nigra
25%
Acute Cocaine
25%
Cocaine Users
25%
Protein Level
16%
Age-matched
16%
Ventral Tegmental Area
16%
Cocaine Abuse
16%
Brain Regions
8%
Hippocampus
8%
Control Subjects
8%
Protein Expression
8%
Oxidative Stress
8%
Lewy Bodies
8%
Lewy Neurites
8%
Response Change
8%
Neuropathology
8%
Midbrain Dopaminergic Neurons
8%
Drug-free
8%
Hyperthermia
8%
Major Components
8%
Negative Regulator
8%
Agitation
8%
Western Blot
8%
Motor Abnormalities
8%
Causative Agents
8%
Delirium
8%
Synaptic Proteins
8%
Protective Response
8%
Native Protein
8%
Dopamine Turnover
8%
Free Control
8%
Cocaine Exposure
8%
Dopamine Cells
8%
Paranoia
8%
Neuroscience
Synuclein
100%
Parkinson's Disease
25%
Substantia nigra
25%
Ventral Tegmental Area
16%
Cocaine Abuse
16%
Hippocampus
8%
Protein Expression
8%
Neurite
8%
Western Blot
8%
Oxidative Stress
8%
Lewy Body
8%
Midbrain
8%
Delirium
8%
Messenger RNA
8%
Brain Region
8%