Co-survival of the fittest few: Mosaic amplification of receptor tyrosine kinases in glioblastoma

Research output: Contribution to journalComment/debate

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Abstract

Mosaic amplification of receptor tyrosine kinases in glioblastoma suggests that tumor cells with different progression driver mutations may coevolve rather than compete during clonal evolution.

Original languageEnglish
Article number141
JournalGenome biology
Volume13
Issue number1
DOIs
StatePublished - Jan 30 2012

Keywords

  • Clonal evolution
  • Glioblastoma
  • Mosaic amplification
  • Progression driver mutations
  • Receptor tyrosine kinases
  • Tumor heterogeneity

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