Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue

Patrick D. Kumavor; Umar Alqasemi; Behnoosh Tavakoli; Hai Li; Yi Yang; Xiaoguang Sun; Edward Warych; Quing Zhu

doi:10.1002/jbio.201200163

Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue

Patrick D. Kumavor
, Umar Alqasemi
, Behnoosh Tavakoli
, Hai Li
, Yi Yang
, Xiaoguang Sun
, Edward Warych
, Quing Zhu

Department of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

We present the design and construction of a prototype imaging probe capable of co-registered pulse-echo ultrasound and photoacoustic (optoacoustic) imaging in real time. The probe consists of 36 fibers of 200 micron core diameter each that are distributed around a commercial transvaginal ultrasound transducer, and housed in a protective shield. Its performance was demonstrated by two sets of experiments. The first set involved imaging of blood flowing through a tube mimicking a blood vessel, the second set involved imaging of human ovaries ex vivo. The results suggest that the system along with the probe has great potential for imaging and characterizing of ovarian tissue in vivo.

Original language	English
Pages (from-to)	475-484
Number of pages	10
Journal	Journal of Biophotonics
Volume	6
Issue number	6-7
DOIs	https://doi.org/10.1002/jbio.201200163
State	Published - Jun 2013

Keywords

Co-registered ultrasound and photoacoustic imaging
Fiber assembly for high energy delivery
Optoacoustic imaging
Ovarian tissue characterization
Photoacoustic probe and system

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10.1002/jbio.201200163

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title = "Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue",

abstract = "We present the design and construction of a prototype imaging probe capable of co-registered pulse-echo ultrasound and photoacoustic (optoacoustic) imaging in real time. The probe consists of 36 fibers of 200 micron core diameter each that are distributed around a commercial transvaginal ultrasound transducer, and housed in a protective shield. Its performance was demonstrated by two sets of experiments. The first set involved imaging of blood flowing through a tube mimicking a blood vessel, the second set involved imaging of human ovaries ex vivo. The results suggest that the system along with the probe has great potential for imaging and characterizing of ovarian tissue in vivo.",

keywords = "Co-registered ultrasound and photoacoustic imaging, Fiber assembly for high energy delivery, Optoacoustic imaging, Ovarian tissue characterization, Photoacoustic probe and system",

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doi = "10.1002/jbio.201200163",

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AU - Kumavor, Patrick D.

AU - Alqasemi, Umar

AU - Tavakoli, Behnoosh

AU - Li, Hai

AU - Yang, Yi

AU - Sun, Xiaoguang

AU - Warych, Edward

AU - Zhu, Quing

PY - 2013/6

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N2 - We present the design and construction of a prototype imaging probe capable of co-registered pulse-echo ultrasound and photoacoustic (optoacoustic) imaging in real time. The probe consists of 36 fibers of 200 micron core diameter each that are distributed around a commercial transvaginal ultrasound transducer, and housed in a protective shield. Its performance was demonstrated by two sets of experiments. The first set involved imaging of blood flowing through a tube mimicking a blood vessel, the second set involved imaging of human ovaries ex vivo. The results suggest that the system along with the probe has great potential for imaging and characterizing of ovarian tissue in vivo.

AB - We present the design and construction of a prototype imaging probe capable of co-registered pulse-echo ultrasound and photoacoustic (optoacoustic) imaging in real time. The probe consists of 36 fibers of 200 micron core diameter each that are distributed around a commercial transvaginal ultrasound transducer, and housed in a protective shield. Its performance was demonstrated by two sets of experiments. The first set involved imaging of blood flowing through a tube mimicking a blood vessel, the second set involved imaging of human ovaries ex vivo. The results suggest that the system along with the probe has great potential for imaging and characterizing of ovarian tissue in vivo.

KW - Co-registered ultrasound and photoacoustic imaging

KW - Fiber assembly for high energy delivery

KW - Optoacoustic imaging

KW - Ovarian tissue characterization

KW - Photoacoustic probe and system

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Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue

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Keywords

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