Cmv1 and natural killer cell responses to murine cytomegalovirus infection

A. A. Scalzo, W. M. Yokoyama

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

35 Scopus citations

Abstract

The dissection of genetic resistance to murine cytomegalovirus infection in inbred laboratory mouse strains led to the identification of a natural killer cell activation receptor that recognizes a virus-encoded protein. Herein, we summarize the genetic approach and findings that have provided novel insights into innate immune control of virus infections.

Original languageEnglish
Title of host publicationImmunology, Phenotype First
Subtitle of host publicationHow Mutations Have Established New Principles and Pathways in Immunology
EditorsBruce Beutler
Pages101-122
Number of pages22
DOIs
StatePublished - 2008

Publication series

NameCurrent Topics in Microbiology and Immunology
Volume321
ISSN (Print)0070-217X

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