Cloning of the Arabidopsis RTM1 gene, which controls restriction of long-distance movement of tobacco etch virus

  • Stephen T. Chisholm
  • , Sunita K. Mahajan
  • , Steven A. Whitham
  • , Miki L. Yamamoto
  • , James C. Carrington

Research output: Contribution to journalArticlepeer-review

180 Scopus citations

Abstract

The locus RTM1 is necessary for restriction of long-distance movement of tobacco etch virus in Arabidopsis thaliana without causing a hypersensitive response or inducing systemic acquired resistance. The RTM1 gene was isolated by map-based cloning. The deduced gene product is similar to the α-chain of the Artocarpus integrifolla ectin, jacalin, and to several proteins that contain multiple repeats of a jacalin-like sequence. These proteins comprise a family with members containing modular organizations of one or more jacalin repeat units and are implicated in defense against viruses, fungi, and insects.

Original languageEnglish
Pages (from-to)489-494
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume97
Issue number1
DOIs
StatePublished - Jan 4 2000

Keywords

  • Resistance

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