Clonal evolution: Multiregion sequencing of esophageal adenocarcinoma before and after chemotherapy

Siddhartha Devarakonda, Ramaswamy Govindan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

It is possible to decipher the clonal architecture of a tumor and the sequence in which cancer clones acquire genomic alterations through multiregion sequencing (M-seq). Serial evaluation of tumor specimens through M-seq can provide valuable information on the molecular basis of resistance to therapy.

Original languageEnglish
Pages (from-to)796-798
Number of pages3
JournalCancer discovery
Volume5
Issue number8
DOIs
StatePublished - Aug 1 2015

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