Clinicopathological course of acute kidney injury following brown recluse (Loxoscles reclusa) envenomation

Siddiq Anwar, Rafael Torosyan, Charles Ginsberg, Helen Liapis, Aubrey R. Morrison

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We report a case of severe systemic loxoscelism in a previously healthy young man. This was associated with a Coombs-positive hemolytic anemia, striking leukomid reaction, renal failure, respiratory failure and cardiovascular collapse. This is the first documented case of a renal biopsy in a patient with renal failure after envenomation by the brown recluse spider. Associated systemic toxicity usually resolves but requires prompt recognition and supportive care in an intensive care setting. We also discuss the potential mechanism by which the venom of this small spider can lead to multiorgan failure and possibly death.

Original languageEnglish
Pages (from-to)609-612
Number of pages4
JournalClinical Kidney Journal
Issue number6
StatePublished - Dec 2013


  • Acute kidney injury
  • Brown recluse envenomation
  • Coombs-positive hemolytic anemia
  • Loxoscelism
  • Renal biopsy


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