Clinicopathological course of acute kidney injury following brown recluse (Loxoscles reclusa) envenomation

Siddiq Anwar; Rafael Torosyan; Charles Ginsberg; Helen Liapis; Aubrey R. Morrison

doi:10.1093/ckj/sft111

Clinicopathological course of acute kidney injury following brown recluse (Loxoscles reclusa) envenomation

Siddiq Anwar, Rafael Torosyan, Charles Ginsberg, Helen Liapis, Aubrey R. Morrison

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

We report a case of severe systemic loxoscelism in a previously healthy young man. This was associated with a Coombs-positive hemolytic anemia, striking leukomid reaction, renal failure, respiratory failure and cardiovascular collapse. This is the first documented case of a renal biopsy in a patient with renal failure after envenomation by the brown recluse spider. Associated systemic toxicity usually resolves but requires prompt recognition and supportive care in an intensive care setting. We also discuss the potential mechanism by which the venom of this small spider can lead to multiorgan failure and possibly death.

Original language	English
Pages (from-to)	609-612
Number of pages	4
Journal	Clinical Kidney Journal
Volume	6
Issue number	6
DOIs	https://doi.org/10.1093/ckj/sft111
State	Published - Dec 2013

Keywords

Acute kidney injury
Brown recluse envenomation
Coombs-positive hemolytic anemia
Loxoscelism
Renal biopsy

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10.1093/ckj/sft111

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abstract = "We report a case of severe systemic loxoscelism in a previously healthy young man. This was associated with a Coombs-positive hemolytic anemia, striking leukomid reaction, renal failure, respiratory failure and cardiovascular collapse. This is the first documented case of a renal biopsy in a patient with renal failure after envenomation by the brown recluse spider. Associated systemic toxicity usually resolves but requires prompt recognition and supportive care in an intensive care setting. We also discuss the potential mechanism by which the venom of this small spider can lead to multiorgan failure and possibly death.",

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AU - Liapis, Helen

AU - Morrison, Aubrey R.

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AB - We report a case of severe systemic loxoscelism in a previously healthy young man. This was associated with a Coombs-positive hemolytic anemia, striking leukomid reaction, renal failure, respiratory failure and cardiovascular collapse. This is the first documented case of a renal biopsy in a patient with renal failure after envenomation by the brown recluse spider. Associated systemic toxicity usually resolves but requires prompt recognition and supportive care in an intensive care setting. We also discuss the potential mechanism by which the venom of this small spider can lead to multiorgan failure and possibly death.

KW - Acute kidney injury

KW - Brown recluse envenomation

KW - Coombs-positive hemolytic anemia

KW - Loxoscelism

KW - Renal biopsy

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Clinicopathological course of acute kidney injury following brown recluse (Loxoscles reclusa) envenomation

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Keywords

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