Clinical Reasoning: A 6-Year-Old Girl with Right-Sided Pain and Weakness

Cristina M. Gaudioso, Rachel Zolno, Anne Wagner, Soe Mar

Research output: Contribution to journalArticlepeer-review


We outline the case of a 6-year-old girl presenting with a 2-week course of waxing and waning neurologic symptoms, including right-sided pain, weakness, dizziness, and difficulty walking. Her examination was notable for right-sided weakness, hyperreflexia, and dysmetria. Diagnostic evaluation was significant for MRI with numerous T2 hyperintense, T1 hypointense, and T1-enhancing lesions located in the juxtacortical and periventricular regions, corpus callosum, brainstem, and spinal cord; positive CSF oligoclonal bands; negative serum aquaporin-4 immunoglobulin G (IgG) and myelin oligodendrocyte glycoprotein IgG; and positive serum Epstein-Barr viral capsid antigen IgG.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
Issue number2
StatePublished - Jan 10 2023


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