Clinical diagnosis and course of Alzheimer's disease

J. C. Morris, E. H. Rubin

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Alzheimer's disease can be accurately diagnosed by clinical methods alone in about 90% of cases. The adoption of uniform diagnostic criteria and assessment procedures, such as those developed by the Consortium to Establish a Registry for Alzheimer's Disease (CERAD), will likely improve the characterization of the disease across a variety of clinical settings. In general, Alzheimer's disease is a relentlessly progressive disorder; however, it also is clinically heterogeneous. This is underscored by its diverse cognitive deficits, neurologic features, behavioral pathology, and rates of progression.

Original languageEnglish
Pages (from-to)223-236
Number of pages14
JournalPsychiatric Clinics of North America
Volume14
Issue number2
DOIs
StatePublished - 1991

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