Clinical diagnosis and course of Alzheimer's disease

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Alzheimer's disease can be accurately diagnosed by clinical methods alone in about 90% of cases. The adoption of uniform diagnostic criteria and assessment procedures, such as those developed by the Consortium to Establish a Registry for Alzheimer's Disease (CERAD), will likely improve the characterization of the disease across a variety of clinical settings. In general, Alzheimer's disease is a relentlessly progressive disorder; however, it also is clinically heterogeneous. This is underscored by its diverse cognitive deficits, neurologic features, behavioral pathology, and rates of progression.

Original languageEnglish
Pages (from-to)223-236
Number of pages14
JournalPsychiatric Clinics of North America
Issue number2
StatePublished - 1991


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