TY - JOUR
T1 - Classifying Complications
T2 - Assessing Adult Spinal Deformity 2-Year Surgical Outcomes
AU - Klineberg, Eric O.
AU - Passias, Peter G.
AU - Poorman, Gregory W.
AU - Jalai, Cyrus M.
AU - Atanda, Abiola
AU - Worley, Nancy
AU - Horn, Samantha
AU - Sciubba, Daniel M.
AU - Hamilton, D. Kojo
AU - Burton, Douglas C.
AU - Gupta, Munish Chandra
AU - Smith, Justin S.
AU - Soroceanu, Alexandra
AU - Hart, Robert A.
AU - Neuman, Brian
AU - Ames, Christopher P.
AU - Schwab, Frank J.
AU - Lafage, Virginie
N1 - Publisher Copyright:
© The Author(s) 2020.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Study Design: Retrospective review of prospective database. Objective: Complication rates for adult spinal deformity (ASD) surgery vary widely because there is no accepted system for categorization. Our objective was to identify the impact of complication occurrence, minor-major complication, and Clavien-Dindo complication classification (Cc) on clinical variables and patient-reported outcomes. Methods: Complications in surgical ASD patients with complete baseline and 2-year data were considered intraoperatively, perioperatively ('6 weeks), and postoperatively ('6 weeks). Primary outcome measures were complication timing and severity according to 3 scales: complication presence (yes/no), minor-major, and Cc score. Secondary outcomes were surgical outcomes (estimated blood loss [EBL], length of stay [LOS], reoperation) and health-related quality of life (HRQL) scores. Univariate analyses determined complication presence, type, and Cc grade impact on operative variables and on HRQL scores. Results: Of 167 patients, 30.5% (n = 51) had intraoperative, 48.5% (n = 81) had perioperative, and 58.7% (n = 98) had postoperative complications. Major intraoperative complications were associated with increased EBL (P '.001) and LOS (P =.0092). Postoperative complication presence and major postoperative complication were associated with reoperation (P '.001). At 2 years, major perioperative complications were associated with worse ODI, SF-36, and SRS activity and appearance scores (P '.02). Increasing perioperative Cc score and postoperative complication presence were the best predictors of worse HRQL outcomes (P '.05). Conclusion: The Cc Scale was most useful in predicting changes in patient outcomes; at 2 years, patients with raised perioperative Cc scores and postoperative complications saw reduced HRQL improvement. Intraoperative and perioperative complications were associated with worse short-term surgical and inpatient outcomes.
AB - Study Design: Retrospective review of prospective database. Objective: Complication rates for adult spinal deformity (ASD) surgery vary widely because there is no accepted system for categorization. Our objective was to identify the impact of complication occurrence, minor-major complication, and Clavien-Dindo complication classification (Cc) on clinical variables and patient-reported outcomes. Methods: Complications in surgical ASD patients with complete baseline and 2-year data were considered intraoperatively, perioperatively ('6 weeks), and postoperatively ('6 weeks). Primary outcome measures were complication timing and severity according to 3 scales: complication presence (yes/no), minor-major, and Cc score. Secondary outcomes were surgical outcomes (estimated blood loss [EBL], length of stay [LOS], reoperation) and health-related quality of life (HRQL) scores. Univariate analyses determined complication presence, type, and Cc grade impact on operative variables and on HRQL scores. Results: Of 167 patients, 30.5% (n = 51) had intraoperative, 48.5% (n = 81) had perioperative, and 58.7% (n = 98) had postoperative complications. Major intraoperative complications were associated with increased EBL (P '.001) and LOS (P =.0092). Postoperative complication presence and major postoperative complication were associated with reoperation (P '.001). At 2 years, major perioperative complications were associated with worse ODI, SF-36, and SRS activity and appearance scores (P '.02). Increasing perioperative Cc score and postoperative complication presence were the best predictors of worse HRQL outcomes (P '.05). Conclusion: The Cc Scale was most useful in predicting changes in patient outcomes; at 2 years, patients with raised perioperative Cc scores and postoperative complications saw reduced HRQL improvement. Intraoperative and perioperative complications were associated with worse short-term surgical and inpatient outcomes.
KW - Clavien-Dindo Scale
KW - adult spinal deformity
KW - complication classification
KW - complications
KW - major-minor
KW - outcomes
KW - patient-reported outcomes
UR - http://www.scopus.com/inward/record.url?scp=85088843604&partnerID=8YFLogxK
U2 - 10.1177/2192568220937473
DO - 10.1177/2192568220937473
M3 - Article
C2 - 32730730
AN - SCOPUS:85088843604
SN - 2192-5682
VL - 10
SP - 896
EP - 907
JO - Global Spine Journal
JF - Global Spine Journal
IS - 7
ER -