Circadian pacemakers: How clock properties relate to their cellular properties

Paul H. Taghert

doi:10.1016/j.cub.2011.09.041

Circadian pacemakers: How clock properties relate to their cellular properties

Paul H. Taghert

Research output: Contribution to journal › Short survey › peer-review

Abstract

Circadian (∼24 hour) pacemaking mechanisms exist within single cells. Which cellular properties contrive to produce a precise clockworks, and which cell properties are downstream of it? The literature is conflicted as to whether membrane excitability contributes to the mechanism. Now, a new conditional genetic strategy argues excitability is largely dispensable.

Original language	English
Pages (from-to)	R894-R896
Journal	Current Biology
Volume	21
Issue number	21
DOIs	https://doi.org/10.1016/j.cub.2011.09.041
State	Published - Nov 8 2011

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10.1016/j.cub.2011.09.041

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abstract = "Circadian (∼24 hour) pacemaking mechanisms exist within single cells. Which cellular properties contrive to produce a precise clockworks, and which cell properties are downstream of it? The literature is conflicted as to whether membrane excitability contributes to the mechanism. Now, a new conditional genetic strategy argues excitability is largely dispensable.",

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AB - Circadian (∼24 hour) pacemaking mechanisms exist within single cells. Which cellular properties contrive to produce a precise clockworks, and which cell properties are downstream of it? The literature is conflicted as to whether membrane excitability contributes to the mechanism. Now, a new conditional genetic strategy argues excitability is largely dispensable.

UR - https://www.scopus.com/pages/publications/80755168386

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DO - 10.1016/j.cub.2011.09.041

M3 - Short survey

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VL - 21

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JO - Current Biology

JF - Current Biology

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Circadian pacemakers: How clock properties relate to their cellular properties

Abstract

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