@article{0be80e06e3d4469ca98eafe7ae98a657,
title = "CINRG pilot trial of oxatomide in steroid-na{\"i}ve Duchenne muscular dystrophy",
abstract = "The authors report a pilot open-label two-center therapeutic trial of oxatomide in 14 steroid-naive DMD boys aged 5-10 years. Comparison of linear evolutions between 3 months medication-free lead-in periods and 6 months treatment periods showed no significant differences in quantitative (QMT) and manual (MMT) measurements of muscle strength and timed functional tests. A modest mitigation of strength deterioration over time cannot be excluded.",
keywords = "Clinical trial, Duchenne, Muscle, Muscular dystrophy, Oxatomide, Treatment",
author = "Buyse, \{Gunnar M.\} and Nathalie Goemans and Erik Henricson and Alejandro Jara and \{van den Hauwe\}, Marleen and Robert Leshner and Florence, \{Julaine M.\} and Mayhew, \{Jill E.\} and Escolar, \{Diana M.\}",
note = "Funding Information: The authors respectfully and gratefully commemorate the late Dr. Kantilal Patel. This study was supported by a grant from the Muscular Dystrophy Association USA and from the Association Fran{\c c}aise contre les Myopathies. The authors also thank Janssen-Cilag for providing the study drug (Tinset {\textregistered} ), all patients and parents who participated in the study, and Drs. Paula Clemens, Jean Mah and Yoram Nevo for useful discussions. ",
year = "2007",
month = nov,
doi = "10.1016/j.ejpn.2007.02.009",
language = "English",
volume = "11",
pages = "337--340",
journal = "European Journal of Paediatric Neurology",
issn = "1090-3798",
number = "6",
}