Circadian rhythms, endogenous and entrainable adaptations to 24-hour cycles of light and dark, influence almost all physiologic functions. Emerging evidence suggests that the disruption of normal circadian rhythms, termed chronodisruption, could affect a wide range of disease-related processes. In this review, we describe the molecular generation of circadian rhythms, the effects of chronodisruption on human health, the circadian timing of birth in multiple species, the possible effects of chronodisruption on preterm birth, and some of the open questions in this field.

Original languageEnglish
Pages (from-to)60-67
Number of pages8
JournalBest Practice and Research: Clinical Obstetrics and Gynaecology
StatePublished - Oct 2018


  • Chronodisruption
  • Circadian rhythms
  • Pregnancy
  • Preterm birth


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