Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing

M. Teresa Magone; Robert E. Nasser; A. Vicky Cevallos; Todd P. Margolis

doi:10.1016/j.ajo.2004.12.014

Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing

M. Teresa Magone, Robert E. Nasser, A. Vicky Cevallos, Todd P. Margolis

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

PURPOSE: To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN: Case report. METHODS: Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS: A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued. CONCLUSIONS: Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.

Original language	English
Pages (from-to)	1135-1136
Number of pages	2
Journal	American journal of ophthalmology
Volume	139
Issue number	6
DOIs	https://doi.org/10.1016/j.ajo.2004.12.014
State	Published - Jun 2005

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title = "Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing",

abstract = "PURPOSE: To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN: Case report. METHODS: Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS: A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued. CONCLUSIONS: Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.",

author = "Magone, {M. Teresa} and Nasser, {Robert E.} and Cevallos, {A. Vicky} and Margolis, {Todd P.}",

year = "2005",

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T1 - Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing

AU - Magone, M. Teresa

AU - Nasser, Robert E.

AU - Cevallos, A. Vicky

AU - Margolis, Todd P.

PY - 2005/6

Y1 - 2005/6

N2 - PURPOSE: To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN: Case report. METHODS: Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS: A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued. CONCLUSIONS: Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.

AB - PURPOSE: To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN: Case report. METHODS: Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS: A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued. CONCLUSIONS: Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.

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AN - SCOPUS:20444449687

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SP - 1135

EP - 1136

JO - American journal of ophthalmology

JF - American journal of ophthalmology

IS - 6

ER -

Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing

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