TY - JOUR
T1 - Chronic progressive external ophthalmoplegia in the absence of ptosis
AU - Bucelli, Robert C.
AU - Lee, Michael S.
AU - McClelland, Collin M.
PY - 2016/8/23
Y1 - 2016/8/23
N2 - Classically defined as bilateral, symmetric, and progressive ophthalmoparesis with myopathic ptosis, chronic progressive external ophthalmoplegia (CPEO) rarely has been reported in the absence of ptosis. We describe 2 patients with CPEO and without ptosis who presented with binocular diplopia related to small-angle esodeviations, poor fusional amplitudes, and slow saccades. In both cases, hematological studies and neuroimaging ruled out alternative etiologies, whereas muscle biopsy showed findings of mitochondrial myopathy.
AB - Classically defined as bilateral, symmetric, and progressive ophthalmoparesis with myopathic ptosis, chronic progressive external ophthalmoplegia (CPEO) rarely has been reported in the absence of ptosis. We describe 2 patients with CPEO and without ptosis who presented with binocular diplopia related to small-angle esodeviations, poor fusional amplitudes, and slow saccades. In both cases, hematological studies and neuroimaging ruled out alternative etiologies, whereas muscle biopsy showed findings of mitochondrial myopathy.
UR - http://www.scopus.com/inward/record.url?scp=84964270631&partnerID=8YFLogxK
U2 - 10.1097/WNO.0000000000000384
DO - 10.1097/WNO.0000000000000384
M3 - Article
C2 - 27111092
AN - SCOPUS:84964270631
SN - 1070-8022
VL - 36
SP - 270
EP - 274
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
IS - 3
ER -