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Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019

  • William G. Wierda
  • , John C. Byrd
  • , Jeremy S. Abramson
  • , Syed F. Bilgrami
  • , Greg Bociek
  • , Danielle Brander
  • , Jennifer Brown
  • , Asher A. Chanan-Khan
  • , Julio C. Chavez
  • , Steve E. Coutre
  • , Randall S. Davis
  • , Christopher D. Fletcher
  • , Brian Hill
  • , Brad S. Kahl
  • , Manali Kamdar
  • , Lawrence D. Kaplan
  • , Nadia Khan
  • , Thomas J. Kipps
  • , Shuo Ma
  • , Sami Malek
  • Anthony Mato, Claudio Mosse, Vishala T. Neppalli, Mazyar Shadman, Tanya Siddiqi, Deborah Stephens, Nina Wagner, Mary A. Dwyer, Hema Sundar

Research output: Contribution to journalArticlepeer-review

Abstract

Chronic lymphocytic leukemia (CLL) is generally characterized by an indolent disease course. Histologic transformation (also known as Richter’s transformation) to more aggressive lymphomas, such as diffuse large B-cell lymphoma or Hodgkin lymphoma, occurs in approximately 2% to 10% of patients and is associated with a poor prognosis. These NCCN Guidelines Insights discuss the recommendations for the diagnosis and management of patients with histologic transformation.

Original languageEnglish
Pages (from-to)12-20
Number of pages9
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume17
Issue number1
DOIs
StatePublished - Jan 2019

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