TY - JOUR
T1 - Chronic intraaneurysmal pressure measurement
T2 - An experimental method for evaluating the effectiveness of endovascular aortic aneurysm exclusion
AU - Sanchez, L. A.
AU - Faries, P. L.
AU - Marin, M. L.
AU - Ohki, T.
AU - Parsons, R. E.
AU - Marty, B.
AU - Soeiro, D.
AU - Olivieri, S.
AU - Veith, F. J.
N1 - Funding Information:
Supported by grants from the U.S. Public Health Service (HL 02990-03), the James Hilton Manning and Emma Austin Manning Foundation, the Anna S. Brown Trust, the New York Institute for Vascular Studies, and a grant from the Boston Scientific Corporation, Watertown, Mass.
PY - 1997
Y1 - 1997
N2 - Purpose: To evaluate and compare the intraaneurysmal pressure (LAP) after exclusion using two different endovascular grafts. Methods: Eight mongrel dogs had a 3 x 3 cm polytetrafluoroethylene (PTFE) aneurysm sewn as an interposition graft of the infrarenal aorta. A pressure transducer implanted into the aneurysm wall permitted continuous electronic IAP monitoring. Four aneurysms were excluded with a transluminally placed endovascular graft made of a PTFE graft and two Palmaz stents (PTFE-EG), three were excluded with a tantalum-Dacron endovascular graft (TD-EG), and one was surgically treated with a standard PTFE graft (PTFE-Surg). The dogs were observed for 18 to 50 days (mean, 37.5 days) and were evaluated after surgery with duplex and spiral computed tomographic scans. Results: All grafts successfully excluded the aneurysms without perigraft channels or leaks as documented by arteriogram and duplex and computed tomographic scans. The mean IAPs after repair with all PTFE-EGs were significantly lower (p < 0.001) than the mean systemic pressures. In addition, the mean IAP reduction was significantly greater (P < 0.005) in the PTFE-EG group than in the TD-EG group. Conclusions: Aneurysm exclusion with PTFE-EG significantly lowered IAP, did so significantly better than the TD-EG, and approached the IAP reduction obtained by standard repair. Such pressure reduction is necessary for effective protection against aneurysm rupture.
AB - Purpose: To evaluate and compare the intraaneurysmal pressure (LAP) after exclusion using two different endovascular grafts. Methods: Eight mongrel dogs had a 3 x 3 cm polytetrafluoroethylene (PTFE) aneurysm sewn as an interposition graft of the infrarenal aorta. A pressure transducer implanted into the aneurysm wall permitted continuous electronic IAP monitoring. Four aneurysms were excluded with a transluminally placed endovascular graft made of a PTFE graft and two Palmaz stents (PTFE-EG), three were excluded with a tantalum-Dacron endovascular graft (TD-EG), and one was surgically treated with a standard PTFE graft (PTFE-Surg). The dogs were observed for 18 to 50 days (mean, 37.5 days) and were evaluated after surgery with duplex and spiral computed tomographic scans. Results: All grafts successfully excluded the aneurysms without perigraft channels or leaks as documented by arteriogram and duplex and computed tomographic scans. The mean IAPs after repair with all PTFE-EGs were significantly lower (p < 0.001) than the mean systemic pressures. In addition, the mean IAP reduction was significantly greater (P < 0.005) in the PTFE-EG group than in the TD-EG group. Conclusions: Aneurysm exclusion with PTFE-EG significantly lowered IAP, did so significantly better than the TD-EG, and approached the IAP reduction obtained by standard repair. Such pressure reduction is necessary for effective protection against aneurysm rupture.
UR - https://www.scopus.com/pages/publications/0030818762
U2 - 10.1016/S0741-5214(97)70182-4
DO - 10.1016/S0741-5214(97)70182-4
M3 - Article
C2 - 9279308
AN - SCOPUS:0030818762
SN - 0741-5214
VL - 26
SP - 222
EP - 230
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
IS - 2
ER -