Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance

Keyphrases

• Chromatin 100%
• High Mobility Group Box 1 (HMGB1) 100%
• Inflammatory Genes 100%
• Linker Histone 100%
• Endotoxin Tolerance 100%
• Tumor Necrosis Factor-α 75%
• NF-B 25%
• Heterochromatin 25%
• Severe Inflammation 25%
• Interleukin-1β 16%
• Leukocytes 16%
• Endotoxin 16%
• RelB 16%
• Histone H3K9 16%
• H3K9 Methylation 16%
• Epigenetics 8%
• Knockdown 8%
• MRNA Level 8%
• Dissociation 8%
• Transcriptional Repressor 8%
• Linker 8%
• Small Interfering RNA (siRNA) 8%
• Transcriptional Repression 8%
• Repressor 8%
• Gene-specific 8%
• Epigenetic Silencing 8%
• Chromatin Modification 8%
• Epigenetic Signature 8%
• THP1 8%
• Transcriptionally Active 8%
• Histone H1 8%
• Interleukin 8%
• Euchromatin 8%
• Histone Methylation 8%
• Nucleosomal DNA 8%
• Promonocytes 8%

Biochemistry, Genetics and Molecular Biology

• High-Mobility Group 100%
• Histone H1 100%
• Tumor Necrosis Factor 75%
• Tumor Necrosis Factor Alpha 75%
• Promoter Region 33%
• Transcription 33%
• Epigenetics 25%
• Heterochromatin 25%
• Leukocyte 16%
• Interleukin-1 16%
• Nucleosome 16%
• Histone 16%
• Cytokine 8%
• Small Interfering RNA 8%
• Repressor 8%
• Euchromatin 8%
• Histone Methylation 8%
• Promonocyte 8%
• Messenger RNA 8%

Immunology and Microbiology

• Tumor Necrosis Factor Alpha 100%
• Histone 100%
• Promoter Region 44%
• Systemic Inflammation 33%
• Heterochromatin 33%
• Leukocyte 22%
• Interleukin-1 22%
• Nucleosome 22%
• Cytokine 11%
• Repressor Gene 11%
• Histone Methylation 11%
• Euchromatin 11%
• Promonocyte 11%