Choroidal neovascular membrane associated with optic nerve coloboma in a patient with CHARGE association

Medhat F. Guirgis, Gregg T. Lueder

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Purpose: To report a patient with CHARGE association (coloboma, heart disease, choanal atresia, growth retardation, genital hypoplasia, and ear abnormalities) who developed a choroidal neovascular membrane in association with an optic nerve coloboma. Design: Interventional/observational case report. Methods: A 21-month-old boy with CHARGE association developed a grayish choroidal neovascular membrane associated with lipid exudation, subretinal fluid, and retinal hemorrhage at the temporal edge of his right optic nerve coloboma. Results: The patient underwent transpupillary diode laser of the choroidal neovascular membrane. Five months later, it and the serous retinal detachment had resolved. Conclusions: Patients with CHARGE association may develop choroidal neovascular membrane with serous retinal detachments in association with optic nerve colobomas. These neovascular membranes may be treated successfully with transpupillary diode laser.

Original languageEnglish
Pages (from-to)919-920
Number of pages2
JournalAmerican journal of ophthalmology
Volume135
Issue number6
DOIs
StatePublished - Jun 1 2003

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