Gene therapy to correct defective genes requires efficient gene delivery and long-term gene expression. The vector systems currently available have not allowed the simultaneous provision of both of these goals. Several groups are now developing chimeric viral vector systems that incorporate the favorable attributes of two different viral vectors. These chimeric vectors might allow the goals for specific gene therapy applications to be realized.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalMolecular Medicine Today
Issue number1
StatePublished - 1999


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