TY - JOUR
T1 - Childhood diet and growth in boys in relation to timing of puberty and adult height
T2 - the Longitudinal Studies of Child Health and Development
AU - Alimujiang, Aliya
AU - Colditz, Graham A.
AU - Gardner, Jane D.
AU - Park, Yikyung
AU - Berkey, Catherine S.
AU - Sutcliffe, Siobhan
N1 - Funding Information:
Funding AA, GAC, and CSB were supported by the Breast Cancer Research Foundation. YP and SS were supported by the Foundation for Barnes-Jewish Hospital and the Alvin J. Siteman Cancer Center (P30 CA091842). The funders had no role in the study design, data collection, analysis, interpretation of data, preparation of the report, or decision to publish. All authors had full access to the data and analyses, and had final responsibility for the decision to submit for publication.
Publisher Copyright:
© 2018, Springer Nature Switzerland AG.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Purpose: To begin to explore the possible roles of childhood diet and growth in prostate cancer (PCa) development, we investigated these exposures in relation to two known/suspected PCa risk factors, earlier pubertal timing and greater attained height, in the Longitudinal Studies of Child Health and Development. Methods: We used biannual/annual height, weight, and dietary history data to investigate childhood diet, body mass index (BMI), birth length, and childhood height in relation to PCa risk factors (age at peak height velocity (APHV), height at age 13, and adult height) for 64 Caucasian American boys. Results: In adjusted models, childhood fat and animal protein intake was positively associated with height at age 13 and adult height (P < 0.05). A childhood diet high in fat and animal protein and low in vegetable protein was also associated with earlier APHV (P < 0.05), whereas no associations were observed for childhood energy intake or BMI. Birth length and childhood height were positively associated with height at age 13 and adult height, and childhood height was inversely associated with APHV (P < 0.05). Conclusion: Our findings suggest that both childhood diet and growth potential/growth contribute to earlier pubertal timing and taller attained height in males, supporting roles of these factors in PCa development.
AB - Purpose: To begin to explore the possible roles of childhood diet and growth in prostate cancer (PCa) development, we investigated these exposures in relation to two known/suspected PCa risk factors, earlier pubertal timing and greater attained height, in the Longitudinal Studies of Child Health and Development. Methods: We used biannual/annual height, weight, and dietary history data to investigate childhood diet, body mass index (BMI), birth length, and childhood height in relation to PCa risk factors (age at peak height velocity (APHV), height at age 13, and adult height) for 64 Caucasian American boys. Results: In adjusted models, childhood fat and animal protein intake was positively associated with height at age 13 and adult height (P < 0.05). A childhood diet high in fat and animal protein and low in vegetable protein was also associated with earlier APHV (P < 0.05), whereas no associations were observed for childhood energy intake or BMI. Birth length and childhood height were positively associated with height at age 13 and adult height, and childhood height was inversely associated with APHV (P < 0.05). Conclusion: Our findings suggest that both childhood diet and growth potential/growth contribute to earlier pubertal timing and taller attained height in males, supporting roles of these factors in PCa development.
KW - Body size
KW - Childhood diet
KW - Height
KW - Prostate cancer
KW - Puberty
UR - http://www.scopus.com/inward/record.url?scp=85051739542&partnerID=8YFLogxK
U2 - 10.1007/s10552-018-1068-2
DO - 10.1007/s10552-018-1068-2
M3 - Article
C2 - 30109531
AN - SCOPUS:85051739542
SN - 0957-5243
VL - 29
SP - 915
EP - 926
JO - Cancer Causes and Control
JF - Cancer Causes and Control
IS - 10
ER -