Chemistry and Theranostic applications of radiolabeled nanoparticles for cardiovascular, oncological, and pulmonary research

Yunjun Guo, Tolulope Aweda, Kvar C.L. Black, Yongjian Liu

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Labeling nanoparticles with radionuclides has been widely used to form multifunctional and multivalency agents for various biomedical applications. A variety of nanostructures including inorganic, organic and lipid nanoparticles have been labeled with positron or gamma emitting radioisotopes through versatile radiochemistry in a number of disease models to track their in vivo fate, image biomarkers, and monitor treatment response. This review briefly summarizes the recent applications of nanoparticles labeled with radionuclides for oncological, cardiovascular, and pulmonary theranostics.

Original languageEnglish
Pages (from-to)470-478
Number of pages9
JournalCurrent Topics in Medicinal Chemistry
Volume13
Issue number4
DOIs
StatePublished - Jun 14 2013

Keywords

  • Cardiology
  • Lung
  • Nanoparticles
  • Oncology
  • Radiolabeling
  • Theranostics

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