Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy

Farnoush Forghani, Taylor Patton, Jennifer Kwak, David Thomas, Quentin Diot, Chad Rusthoven, Richard Castillo, Edward Castillo, Inga Grills, Thomas Guerrero, Moyed Miften, Yevgeniy Vinogradskiy

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

This study investigates agreement between ventilation and perfusion for lung cancer patients undergoing radiotherapy. Ventilation-perfusion scans of nineteen patients with stage III lung cancer from a prospective protocol were compared using voxel-wise Spearman correlation-coefficients. The presented results show in about 25% of patients, ventilation and perfusion exhibit lower agreement.

Original languageEnglish
Pages (from-to)120-124
Number of pages5
JournalRadiotherapy and Oncology
Volume160
DOIs
StatePublished - Jul 2021

Keywords

  • 4DCT scans
  • Dice Similarity
  • Functional avoidance
  • Lung cancer
  • SPECT ventilation/perfusion
  • Spearman correlation

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