Characterization of the proton irradiation induced luminescence of materials and application in radiation oncology dosimetry

Arash Darafsheh, Rongxiao Zhang, Alireza Kassaee, Jarod C. Finlay

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations


Visible light generated as the result of interaction of ionizing radiation with matter can be used for radiation therapy quality assurance. In this work, we characterized the visible light observed during proton irradiation of poly(methyl methacrylate) (PMMA) and silica glass fiber materials by performing luminescence spectroscopy. The spectra of the luminescence signal from PMMA and silica glass fibers during proton irradiation showed continuous spectra whose shape were different from that expected from Čerenkov radiation, indicating that Čerenkov radiation cannot be the responsible radioluminescence signal. The luminescence signal from each material showed a Bragg peak pattern and their corresponding proton ranges are in agreement with measurements performed by a standard ion chamber. The spectrum of the silica showed two peaks at 460 and 650 nm stem from the point defects of the silica: oxygen deficiency centers (ODC) and non-bridging oxygen hole centers (NBOHC), respectively. The spectrum of the PMMA fiber showed a continuous spectrum with a peak at 410 nm whose origin is connected with the fluorescence of the PMMA material. Our results are of interest for various applications based on imaging radioluminescent signal in proton therapy and will inform on the design of high-resolution fiber probes for proton therapy dosimetry.

Original languageEnglish
Title of host publicationMolecular-Guided Surgery
Subtitle of host publicationMolecules, Devices, and Applications IV
EditorsSylvain Gioux, Brian W. Pogue
ISBN (Electronic)9781510614413
StatePublished - 2018
EventMolecular-Guided Surgery: Molecules, Devices, and Applications IV 2018 - San Francisco, United States
Duration: Jan 27 2018Jan 29 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMolecular-Guided Surgery: Molecules, Devices, and Applications IV 2018
Country/TerritoryUnited States
CitySan Francisco


  • Dosimetry
  • Optical fiber
  • Proton therapy
  • Radioluminescence
  • Spectroscopy
  • Čerenkov radiation


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