@inproceedings{ea16d9d0f0b54bd8bcfa8e6f5cb22186,
title = "Characterization of rare-earth-doped nanophosphors for photodynamic therapy excited by clinical ionizing radiation beams",
abstract = "We investigated the optical properties of novel terbium (Tb3+)-doped nanophosphors with various host compounds irradiated by clinical electron, photon, and proton beams for their potential as optical probes. The emission spectra of nanophosphors embedded in tissue-mimicking phantoms were collected by an optical fiber connected to a CCD-coupled spectrograph while the samples were irradiated with electron and photon beams generated by a medical linear accelerator and proton beams generated by a clinical cyclotron. We characterized the luminescence of such nanophosphors as a function of the beam energy and observed a dose dependency of the luminescence signal. We demonstrated X-ray luminescence, cathodoluminescence, and ionoluminescence of the nanophosphors in clinical ionizing radiation fields, which indicates their potential as downconverters of high-energy radiation into visible light.",
keywords = "Nanocrystal, dosimetry, ionizing radiation, nanophosphor, photodynamic therapy., terbium",
author = "Arash Darafsheh and Stan Najmr and Taejong Paik and Tenuto, {Michael E.} and Murray, {Christopher B.} and Finlay, {Jarod C.} and Friedberg, {Joseph S.}",
note = "Publisher Copyright: {\textcopyright} 2015 SPIE.; Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIV ; Conference date: 07-02-2015 Through 09-02-2015",
year = "2015",
doi = "10.1117/12.2079373",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Kessel, {David H.} and Tayyaba Hasan",
booktitle = "Optical Methods for Tumor Treatment and Detection",
}