Characterization of ovarian tissue using polarization-sensitive optical coherence tomography

  • Tianheng Wang
  • , Yi Yang
  • , Xiaohong Wang
  • , Melinda Sanders
  • , Molly Brewer
  • , Quing Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We characterized ovarian tissue by using polarization-sensitive optical coherence tomography (PS-OCT). Phase retardation changing rate along with optical scattering coefficient and phase retardation were extracted from 33 ex vivo human ovaries from 18 patients. By using phase retardation changing rate as a classifier, we could achieve 71% sensitivity and 100% specificity. Combining those three parameters together, we could achieve 100% sensitivity and 100% specificity. These initial results showed that the quantitative analysis of PS-OCT could be a useful tool to characterize normal and malignant ovarian tissue.

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
DOIs
StatePublished - 2013
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, CA, United States
Duration: Feb 4 2013Feb 6 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8571
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
Country/TerritoryUnited States
CitySan Francisco, CA
Period02/4/1302/6/13

Keywords

  • optical scattering coefficient
  • ovarian tissue
  • phase retardation
  • phase retardation changing rate
  • polarization-sensitive optical coherence tomography

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