The structures of α1,2-mannose containing partially processed asparagine-linked oligosaccharides on the α-chain of MOPC 315 IgA were characterized using specific glycosidases and acetolysis. Man6GlcNAc2, a substrate for a Golgi α1,2-mannosidase, was found to be a single isomeric structure. Likewise, Man7-9GlcNAc2 were single isomers indicating an ordered sequence of removal of α1,2-linked mannose residues on this murine immunoglobulin heavy chain.
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Apr 30 1985|