TY - JOUR
T1 - Characterization of MOPC 315 IgA oligosaccharide processing intermediates
AU - Hickman, Scot
AU - Theodorakis, Janice L.
PY - 1985/4/30
Y1 - 1985/4/30
N2 - The structures of α1,2-mannose containing partially processed asparagine-linked oligosaccharides on the α-chain of MOPC 315 IgA were characterized using specific glycosidases and acetolysis. Man6GlcNAc2, a substrate for a Golgi α1,2-mannosidase, was found to be a single isomeric structure. Likewise, Man7-9GlcNAc2 were single isomers indicating an ordered sequence of removal of α1,2-linked mannose residues on this murine immunoglobulin heavy chain.
AB - The structures of α1,2-mannose containing partially processed asparagine-linked oligosaccharides on the α-chain of MOPC 315 IgA were characterized using specific glycosidases and acetolysis. Man6GlcNAc2, a substrate for a Golgi α1,2-mannosidase, was found to be a single isomeric structure. Likewise, Man7-9GlcNAc2 were single isomers indicating an ordered sequence of removal of α1,2-linked mannose residues on this murine immunoglobulin heavy chain.
UR - http://www.scopus.com/inward/record.url?scp=0021807047&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(85)90086-5
DO - 10.1016/0006-291X(85)90086-5
M3 - Article
C2 - 3922362
AN - SCOPUS:0021807047
SN - 0006-291X
VL - 128
SP - 586
EP - 593
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -