Characterization of materials for optimal near-infrared and x-ray imaging of the breast

Kelly Michaelsen; Venkataramanan Krishnaswamy; Brian W. Pogue; Ken Brooks; Ken Defreitas; Ian Shaw; Steven P. Poplack; Keith D. Paulsen

doi:10.1364/BOE.3.002078

Characterization of materials for optimal near-infrared and x-ray imaging of the breast

Kelly Michaelsen, Venkataramanan Krishnaswamy, Brian W. Pogue, Ken Brooks, Ken Defreitas, Ian Shaw, Steven P. Poplack, Keith D. Paulsen

Department of Radiology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Development of a detector case for complete co-registration of images in a non-fiber-based combined near-infrared spectral tomography and digital breast tomosynthesis, required analysis to find materials that could support a breast under full mammographic compression without affecting the x-ray images or the quality of the near infrared measurements. Several possible solutions were considered, and many types of plastics were tested in the development of the detector case. Light channeling within the detector case changed the data obtained in resin and agarose phantoms, lowering recovered absorption values. Additional developments focusing on blocking stray light were successful and permitted a normal subject imaging exam.

Original language	English
Pages (from-to)	2078-2086
Number of pages	9
Journal	Biomedical Optics Express
Volume	3
Issue number	9
DOIs	https://doi.org/10.1364/BOE.3.002078
State	Published - Sep 1 2012

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AU - Defreitas, Ken

AU - Shaw, Ian

AU - Poplack, Steven P.

AU - Paulsen, Keith D.

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Characterization of materials for optimal near-infrared and x-ray imaging of the breast

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