Characterization of materials for optimal near-infrared and x-ray imaging of the breast

Kelly Michaelsen, Venkataramanan Krishnaswamy, Brian W. Pogue, Ken Brooks, Ken Defreitas, Ian Shaw, Steven P. Poplack, Keith D. Paulsen

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Development of a detector case for complete co-registration of images in a non-fiber-based combined near-infrared spectral tomography and digital breast tomosynthesis, required analysis to find materials that could support a breast under full mammographic compression without affecting the x-ray images or the quality of the near infrared measurements. Several possible solutions were considered, and many types of plastics were tested in the development of the detector case. Light channeling within the detector case changed the data obtained in resin and agarose phantoms, lowering recovered absorption values. Additional developments focusing on blocking stray light were successful and permitted a normal subject imaging exam.

Original languageEnglish
Pages (from-to)2078-2086
Number of pages9
JournalBiomedical Optics Express
Issue number9
StatePublished - Sep 1 2012


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