Abstract
INTRODUCTION: There is a paucity of data on the real-world effectiveness of therapies in patients with Crohn’s disease of the pouch. METHODS: This was a prospective multicenter study evaluating the primary outcome of remission at 12 months of therapy for Crohn’s disease of the pouch. RESULTS: One hundred thirty-four patients were enrolled. Among the 77 patients with symptoms at baseline, 35 (46.7%) achieved remission at 12 months. Of them, 12 (34.3%) changed therapy. There was no significant association between therapy patterns and remission status. DISCUSSION: Approximately 50% with symptoms at enrollment achieved clinical remission at 12 months, most of whom did so without a change in therapy.
Original language | English |
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Pages (from-to) | 584-587 |
Number of pages | 4 |
Journal | American Journal of Gastroenterology |
Volume | 119 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2024 |
Keywords
- colectomy
- ileal pouch anal anastomosis
- therapy
- ulcerative colitis