Changes in relative histone abundance and heterochromatin in αa-crystallin and αb-crystallin knock-in mutant mouse lenses

Keyphrases

• Knock-in Mouse Model 100%
• Histone 100%
• Mouse Lens 100%
• Crystallin 100%
• Mutant Mice 100%
• Heterochromatin 100%
• Electron Microscopy 40%
• Relative Abundance 40%
• Lens Proteins 40%
• Crystallin Gene 40%
• Hereditary Cataract 40%
• Cataract Formation 40%
• RNA Sequencing (RNA-seq) 20%
• Mouse Model 20%
• Autosomal Dominant 20%
• Proteomics 20%
• Mass Spectrometry Analysis 20%
• Adult Mice 20%
• Protein-coding Genes 20%
• Histone H4 20%
• Histone H3 20%
• CRYAB 20%
• αB-crystallin 20%
• High Protein 20%
• Cataract 20%
• Lens nucleus 20%
• Cultured Cells 20%
• Gene Family 20%
• MALDI-TOF 20%
• Age-related Cataract 20%
• Gel Electrophoresis 20%
• Histone H2B 20%
• Single-point mutation 20%
• Mutant Forms 20%
• Identified Genes 20%
• Homozygous mutant 20%
• Histone H2A 20%
• H2A-H2B 20%
• Multigenerational Families 20%
• Objective Understanding 20%
• Nuclei Morphology 20%

Medicine and Dentistry

• Histone 100%
• Heterochromatin 100%
• Crystallin 100%
• Cataract 42%
• Electron Microscopy 28%
• Cataractogenesis 28%
• Lens Protein 28%
• Histone H3 14%
• Histone H4 14%
• Point Mutation 14%
• Lens Nucleus 14%
• Autosomal Dominant Inheritance 14%
• Multigene Family 14%
• Mass Spectrum 14%
• Gel Electrophoresis 14%
• Histone H2B 14%
• Histone H2A 14%
• Matrix-Assisted Laser Desorption-Ionization 14%
• Proteomics 14%

Biochemistry, Genetics and Molecular Biology

• Heterochromatin 100%
• Mouse Mutant 100%
• Histone 100%
• Crystallin 100%
• Electron Microscopy 28%
• Mouse Model 14%
• Autosomal Dominant Inheritance 14%
• Histone H4 14%
• Histone H3 14%
• Point Mutation 14%
• Multigene Family 14%
• Histone H2B 14%
• Histone H2A 14%
• Matrix-Assisted Laser Desorption/Ionization 14%
• Gel Electrophoresis 14%
• Proteomics 14%