Challenges Evaluating Chemotherapy-Induced Peripheral Neuropathy in Childhood Cancer Survivors: Which Instrument Should Nurses Use?

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Abstract

Children treated for cancer are exposed to a variety of chemotherapeutic agents with known toxicity to the peripheral nervous system. The side effect of peripheral neuropathy can cause changes in sensation, function, and even cause pain. Although peripheral neuropathy is recognized by pediatric oncology nurses as an important and significant side effect, measuring neuropathy can be quite complex for clinical care and research efforts. With more children surviving a cancer diagnosis today, this issue is increasingly important for childhood cancer survivors. This article has reviewed existing literature examining peripheral neuropathy in childhood cancer survivors with particular interest paid to measurement tools available and needs for future research. It is important for nurses to choose appropriate measures for clinical care and research methods in order to have an impact on patients experiencing this condition.

Original languageEnglish
Pages (from-to)106-114
Number of pages9
JournalJournal of Pediatric Oncology Nursing
Volume34
Issue number2
DOIs
StatePublished - Mar 1 2017

Keywords

  • childhood cancer survivors
  • late effects
  • peripheral neuropathy
  • peripheral neuropathy measurement

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