Cerebral mucormycosis: Proton MR spectroscopy and MR imaging

Justin A. Siegal, Edwin D. Cacayorinb, A. Sami Nassif, Donna Rizk, Csaba Galambos, Beth Levy, Donald Kennedy, J. Visconti, William Perman

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26 Scopus citations

Abstract

Proton magnetic resonance spectroscopy (MRS) was integrated with magnetic resonance imaging (MRI) in the evaluation of a case of cerebral mucormycosis. MRS showed markedly elevated lactate, depleted N-acetyl aspartate and metabolite resonances attributable to succinate and acetate. The spectroscopy profile is essentially similar to that of bacterial abscess but without the commonly seen resonances of the amino acids valine, leucine and isoleucine. Our extensive literature review did not yield any reports of MRS findings on cerebral mucormycosis. MRS prospectively limited the differential diagnoses given the otherwise nonspecific and complex MR imaging findings in our immunosuppressed patient. (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)915-920
Number of pages6
JournalMagnetic Resonance Imaging
Volume18
Issue number7
DOIs
StatePublished - Oct 24 2000

Keywords

  • Fungus
  • Immunosuppression
  • Magnetic resonance spectroscopy (MRS)
  • Mucormycosis

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    Siegal, J. A., Cacayorinb, E. D., Nassif, A. S., Rizk, D., Galambos, C., Levy, B., Kennedy, D., Visconti, J., & Perman, W. (2000). Cerebral mucormycosis: Proton MR spectroscopy and MR imaging. Magnetic Resonance Imaging, 18(7), 915-920. https://doi.org/10.1016/S0730-725X(00)00180-6