Cerebral Metabolism and Blood Flow

W. J. Powers; A. R. Zazulia

doi:10.1016/B978-0-12-385157-4.00409-7

Cerebral Metabolism and Blood Flow

W. J. Powers, A. R. Zazulia

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

Abstract

Under normal circumstances, the brain relies on energy generated from a continuous supply of oxygen and glucose from the blood. The molar ratio is 5.4 rather than 6.0 as expected for complete oxidation of glucose due to the production of a small amount of lactate. Cerebral blood flow (CBF) in gray matter is approximately 4 times higher than in white matter. Autoregulation is effective in maintaining CBF in healthy human subjects over a wide range of blood pressure from 70 to 150. mm Hg.

Original language	English
Title of host publication	Encyclopedia of the Neurological Sciences
Publisher	Elsevier Inc.
Pages	683-684
Number of pages	2
ISBN (Electronic)	9780123851574
ISBN (Print)	9780123851581
DOIs	https://doi.org/10.1016/B978-0-12-385157-4.00409-7
State	Published - Jan 1 2014

Keywords

Autoregulation
Cerebral blood flow
Cerebral metabolism
Glucose metabolism
Oxygen metabolism

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10.1016/B978-0-12-385157-4.00409-7

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title = "Cerebral Metabolism and Blood Flow",

abstract = "Under normal circumstances, the brain relies on energy generated from a continuous supply of oxygen and glucose from the blood. The molar ratio is 5.4 rather than 6.0 as expected for complete oxidation of glucose due to the production of a small amount of lactate. Cerebral blood flow (CBF) in gray matter is approximately 4 times higher than in white matter. Autoregulation is effective in maintaining CBF in healthy human subjects over a wide range of blood pressure from 70 to 150. mm Hg.",

keywords = "Autoregulation, Cerebral blood flow, Cerebral metabolism, Glucose metabolism, Oxygen metabolism",

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AU - Zazulia, A. R.

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AB - Under normal circumstances, the brain relies on energy generated from a continuous supply of oxygen and glucose from the blood. The molar ratio is 5.4 rather than 6.0 as expected for complete oxidation of glucose due to the production of a small amount of lactate. Cerebral blood flow (CBF) in gray matter is approximately 4 times higher than in white matter. Autoregulation is effective in maintaining CBF in healthy human subjects over a wide range of blood pressure from 70 to 150. mm Hg.

KW - Autoregulation

KW - Cerebral blood flow

KW - Cerebral metabolism

KW - Glucose metabolism

KW - Oxygen metabolism

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EP - 684

BT - Encyclopedia of the Neurological Sciences

PB - Elsevier Inc.

ER -

Cerebral Metabolism and Blood Flow

Abstract

Keywords

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