Cerebral Metabolism and Blood Flow

W. J. Powers, A. R. Zazulia

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations


Under normal circumstances, the brain relies on energy generated from a continuous supply of oxygen and glucose from the blood. The molar ratio is 5.4 rather than 6.0 as expected for complete oxidation of glucose due to the production of a small amount of lactate. Cerebral blood flow (CBF) in gray matter is approximately 4 times higher than in white matter. Autoregulation is effective in maintaining CBF in healthy human subjects over a wide range of blood pressure from 70 to 150. mm Hg.

Original languageEnglish
Title of host publicationEncyclopedia of the Neurological Sciences
PublisherElsevier Inc.
Number of pages2
ISBN (Electronic)9780123851574
ISBN (Print)9780123851581
StatePublished - Jan 1 2014


  • Autoregulation
  • Cerebral blood flow
  • Cerebral metabolism
  • Glucose metabolism
  • Oxygen metabolism


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