Cerebral Metabolism and Blood Flow

W. J. Powers, A. R. Zazulia

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

Under normal circumstances, the brain relies on energy generated from a continuous supply of oxygen and glucose from the blood. The molar ratio is 5.4 rather than 6.0 as expected for complete oxidation of glucose due to the production of a small amount of lactate. Cerebral blood flow (CBF) in gray matter is approximately 4 times higher than in white matter. Autoregulation is effective in maintaining CBF in healthy human subjects over a wide range of blood pressure from 70 to 150. mm Hg.

Original languageEnglish
Title of host publicationEncyclopedia of the Neurological Sciences
PublisherElsevier Inc.
Pages683-684
Number of pages2
ISBN (Electronic)9780123851574
ISBN (Print)9780123851581
DOIs
StatePublished - Jan 1 2014

Keywords

  • Autoregulation
  • Cerebral blood flow
  • Cerebral metabolism
  • Glucose metabolism
  • Oxygen metabolism

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    Powers, W. J., & Zazulia, A. R. (2014). Cerebral Metabolism and Blood Flow. In Encyclopedia of the Neurological Sciences (pp. 683-684). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-385157-4.00409-7