Cerebral amyloid angiopathy progressive disruption of the neurovascular unit

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Cellular elements of the neurovascular unit are essential for the physiological functioning of brain vessels. If any of these vascular elements are disturbed the consequences can be dire. Cerebral amyloid angiopathy (CAA), a disorder caused by the accumulation of amyloid in cerebral vessels, provides a case study of progressive neurovascular unit dysfunction leading to failure of vascular reactivity, smooth muscle cell loss, and eventual frank breakdown of vessel integrity resulting in recurrent and sometimes fatal intracerebral hemorrhage.

Original languageEnglish
Pages (from-to)S16-S19
JournalStroke
Volume40
Issue number3 SUPPL. 1
DOIs
StatePublished - Mar 2009

Keywords

  • Amyloid angiography
  • Neurovascular unit

Fingerprint Dive into the research topics of 'Cerebral amyloid angiopathy progressive disruption of the neurovascular unit'. Together they form a unique fingerprint.

  • Cite this