Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents

Zhikai Liu; Yukiko Kimura; Shin ichi Higashijima; David G.C. Hildebrand; Joshua L. Morgan; Martha W. Bagnall

doi:10.1016/j.neuron.2020.08.019

Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents

Zhikai Liu, Yukiko Kimura, Shin ichi Higashijima, David G.C. Hildebrand, Joshua L. Morgan, Martha W. Bagnall

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Though computational models predict how sensory inputs converge in central neurons, it is technically challenging to test these ideas experimentally. With whole-cell recordings in larval zebrafish in vivo, Liu et al. demonstrate that the convergence of similarly or differently tuned vestibular afferents produces more simple or complex postsynaptic tuning, respectively.

Original language	English
Pages (from-to)	748-762.e4
Journal	Neuron
Volume	108
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2020.08.019
State	Published - Nov 25 2020

Keywords

body balance
electrical synapse
feedforward excitation
high-pass tuning
neural computation
sensorimotor transformation
sensory encoding
vestibulospinal neuron

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10.1016/j.neuron.2020.08.019

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title = "Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents",

abstract = "Though computational models predict how sensory inputs converge in central neurons, it is technically challenging to test these ideas experimentally. With whole-cell recordings in larval zebrafish in vivo, Liu et al. demonstrate that the convergence of similarly or differently tuned vestibular afferents produces more simple or complex postsynaptic tuning, respectively.",

keywords = "body balance, electrical synapse, feedforward excitation, high-pass tuning, neural computation, sensorimotor transformation, sensory encoding, vestibulospinal neuron",

author = "Zhikai Liu and Yukiko Kimura and Higashijima, {Shin ichi} and Hildebrand, {David G.C.} and Morgan, {Joshua L.} and Bagnall, {Martha W.}",

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AU - Hildebrand, David G.C.

AU - Morgan, Joshua L.

AU - Bagnall, Martha W.

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KW - high-pass tuning

KW - neural computation

KW - sensorimotor transformation

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Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents

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