Central nervous system intravascular lymphoma leading to rapidly progressive dementia

Christie G. Turin; Kevin Ting; Anthony Bradshaw; S. Richard Dunham; Karen Nunez-Wallace; Shital M. Patel; Priti Dangayach; Stephanie Holdener; Weei Chin Lin

doi:10.1080/08998280.2020.1866943

Central nervous system intravascular lymphoma leading to rapidly progressive dementia

Christie G. Turin, Kevin Ting, Anthony Bradshaw, S. Richard Dunham, Karen Nunez-Wallace, Shital M. Patel, Priti Dangayach, Stephanie Holdener, Weei Chin Lin

Research output: Contribution to journal › Article › peer-review

Abstract

Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.

Original language	English
Pages (from-to)	373-375
Number of pages	3
Journal	Baylor University Medical Center Proceedings
Volume	34
Issue number	3
DOIs	https://doi.org/10.1080/08998280.2020.1866943
State	Published - 2021

Keywords

Intravascular lymphoma
rapidly progressive dementia

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10.1080/08998280.2020.1866943

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title = "Central nervous system intravascular lymphoma leading to rapidly progressive dementia",

abstract = "Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.",

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AU - Turin, Christie G.

AU - Ting, Kevin

AU - Bradshaw, Anthony

AU - Dunham, S. Richard

AU - Nunez-Wallace, Karen

AU - Patel, Shital M.

AU - Dangayach, Priti

AU - Holdener, Stephanie

AU - Lin, Weei Chin

PY - 2021

Y1 - 2021

N2 - Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.

AB - Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.

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KW - rapidly progressive dementia

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JO - Baylor University Medical Center Proceedings

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Central nervous system intravascular lymphoma leading to rapidly progressive dementia

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