Central Nervous System Infections in the Immunocompromised Adult Presenting to the Emergency Department

Robert J. Stephens, Stephen Y. Liang

Research output: Contribution to journalReview articlepeer-review

Abstract

Over the past 2 decades, the population of immunocompromised patients has increased dramatically in the United States. These patients are at elevated risk for both community-acquired and opportunistic central nervous system infections. We review the most common and serious central nervous system pathogens affecting these patients and outline a diagnostic and therapeutic approach to their management in the emergency department. We recommend a broad diagnostic evaluation, including neuroimaging and cerebrospinal fluid studies where appropriate, empiric antimicrobial therapy, and early involvement of subspecialists to provide comprehensive care for these complex patients.

Original languageEnglish
Pages (from-to)101-121
Number of pages21
JournalEmergency Medicine Clinics of North America
Volume39
Issue number1
DOIs
StatePublished - Feb 2021

Keywords

  • CNS infection
  • HIV
  • Immunocompromise
  • Meningitis
  • Transplant

Fingerprint

Dive into the research topics of 'Central Nervous System Infections in the Immunocompromised Adult Presenting to the Emergency Department'. Together they form a unique fingerprint.

Cite this