Particularly prominent during the past year was the analysis of the subcellular compartment in which MHC class II molecules are located. Some investigators also analyzed the site where peptides are generated for MHC class II binding. Studies of invariant chain were particularly important in trying to establish the functional significance of this molecule.

Original languageEnglish
Pages (from-to)63-69
Number of pages7
JournalCurrent Opinion in Immunology
Issue number1
StatePublished - Feb 1992


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