Cellular reprogramming: Chromatin puts on the brake

Piali Sengupta, Tim Schedl

Research output: Contribution to journalShort surveypeer-review

Abstract

Directed reprogramming of differentiated cells allows the generation of specific cell types for therapeutics and can provide unexpected insights into development. A recent study demonstrates that efficient reprogramming of Caenorhabditis elegans germ cells into neurons can be achieved by knocking down a histone chaperone gene and ectopic expression of a terminal selector transcription factor.

Original languageEnglish
Pages (from-to)R157-R159
JournalCurrent Biology
Volume21
Issue number4
DOIs
StatePublished - Feb 22 2011

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