Cellular and Physiological Effects of Arginine in Seniors

Vance L. Albaugh, Melissa K. Stewart, Adrian Barbul

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations


Arginine is a conditionally essential amino acid that plays a number of critical roles in human health and disease. Since discovering arginine to be the nitrogen source for nitric oxide, biomedical research has intensely focused on it and its vasodilatory effects. However, other recent work has highlighted not only these potential cardiovascular benefits of arginine and its metabolites but also the advances in the knowledge of arginine biochemistry, organ-organ trafficking, and insights from clinical studies examining its role of arginine as a therapeutic modality in a variety of disease states. These advances, along with a comprehensive review of arginine biochemistry and physiology, are reviewed within this chapter and aim to highlight this robust area of medical research.

Original languageEnglish
Title of host publicationNutrition and Functional Foods for Healthy Aging
PublisherElsevier Inc.
Number of pages20
ISBN (Electronic)9780128092996
ISBN (Print)9780128053768
StatePublished - Feb 22 2017


  • Arginase
  • Arginine
  • Citrulline
  • Metabolism
  • Nitric oxide
  • Nitric oxide synthase
  • Nutritional physiology


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